{"id":707,"date":"2025-11-18T11:19:30","date_gmt":"2025-11-18T16:19:30","guid":{"rendered":"https:\/\/click2action.com.co\/doctoralvaro\/?page_id=707"},"modified":"2025-11-18T15:49:02","modified_gmt":"2025-11-18T20:49:02","slug":"mir-thype","status":"publish","type":"page","link":"https:\/\/doctoralvarosanabria.com\/en\/mir-thype\/","title":{"rendered":"Mir-thype"},"content":{"rendered":"
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What is mir-THYpe\u00ae?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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What is mir-THYpe\u00ae?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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It is a molecular test based on microRNAs that analyzes fine needle aspiration biopsy (FNAB) material to determine whether a thyroid nodule classified as Bethesda III or IV has benign or malignant characteristics.<\/p>


No new puncture is required: it is performed using the same sample already obtained in the FNA.<\/p>


Key benefits<\/strong><\/p>

  • Avoid unnecessary surgeries: reduce avoidable surgical procedures by up to 75%.<\/li>
  • High diagnostic accuracy: negative predictive value of 96% and positive predictive value of 76%.<\/li>
  • Based on international clinical evidence and recommended by guidelines from the American Thyroid Association (ATA) and NCCN.<\/li>
  • Supports surgical planning: identifies markers associated with aggressive tumors, optimizing therapeutic decision-making.<\/li><\/ul>

    Molecular markers analyzed<\/strong><\/p>

    • miR-375: associated with medullary carcinoma.<\/li>
    • miR-146b: associated with risk of papillary carcinoma.<\/li>
    • BRAF V600E and TERT C228T\/C250T: mutations linked to increased tumor aggressiveness.<\/li><\/ul>

      Molecular markers analyzed<\/strong><\/p>

      • miR-375: associated with medullary carcinoma.<\/li>
      • miR-146b: associated with risk of papillary carcinoma.<\/li>
      • BRAF V600E and TERT C228T\/C250T: mutations linked to increased tumor aggressiveness.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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        Recommended for patients with Bethesda III or IV cytology results, when there is uncertainty about the need for surgery.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

        \u00bfQu\u00e9 es mir-THYpe\u00ae? \u00bfQu\u00e9 es mir-THYpe\u00ae? Es una prueba molecular basada en microARNs que analiza el material de la biopsia por aspiraci\u00f3n (PAAF) para determinar si un n\u00f3dulo tiroideo clasificado como Bethesda III o IV tiene caracter\u00edsticas benignas o malignas. No requiere una nueva punci\u00f3n: se realiza con la misma muestra ya obtenida en la […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-707","page","type-page","status-publish","hentry"],"yoast_head":"\nMir-thype - Doctor \u00c1lvaro Sanabria<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/doctoralvarosanabria.com\/en\/mir-thype\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mir-thype - Doctor \u00c1lvaro Sanabria\" \/>\n<meta property=\"og:description\" content=\"\u00bfQu\u00e9 es mir-THYpe\u00ae? \u00bfQu\u00e9 es mir-THYpe\u00ae? Es una prueba molecular basada en microARNs que analiza el material de la biopsia por aspiraci\u00f3n (PAAF) para determinar si un n\u00f3dulo tiroideo clasificado como Bethesda III o IV tiene caracter\u00edsticas benignas o malignas. 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Es una prueba molecular basada en microARNs que analiza el material de la biopsia por aspiraci\u00f3n (PAAF) para determinar si un n\u00f3dulo tiroideo clasificado como Bethesda III o IV tiene caracter\u00edsticas benignas o malignas. 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